?nucleotide

nucleotide發(fā)音

英：['nju:kl??ta?d]　　美：['nju:kl?r?ta?d]

英：　　美：

nucleotide中文意思翻譯

n. 核苷酸

nucleotide詞形變化

形容詞: nu-cleosomal |

nucleotide常見例句

1 、UDP stands for Uridine-diphosphate, a phosphorilated derivative of the nucleotide Uridine found in RNA (not DNA).───UDP對尿苷二**酸的立場，**酸化核苷衍生物。在RNA（不是DNA）中發(fā)現(xiàn)尿苷。

2 、PCR-SSCP technique is an important method in Single nucleotide polymorphism analysis .───SSCP是單核苷酸多態(tài)性分析的一項重要技術(shù)。

3 、There was high degree of homology in nucleotide sequence between the PCR expandedATCC 10031 acrAB gene sections and the corresponding ones in Escherichia coli.───PCR擴增的 ATCC 10031的 acrAB基因片段同大腸埃希菌acrAB基因相應(yīng)片段,在核苷 序列上具有很高的同源性。

4 、The information inside a DNA molecule is encoded by the nucleotide bases adenine, thymine, guanine and cytosine (A, T, G and C).───DNA分子攜帶的資訊是由核苷酸堿基腺嘌呤（A）、胸腺嘧啶（T）、鳥嘌呤（G）及胞嘧啶（C）所編寫。

5 、And then we're going to turn and new nucleotides are going to come in and they're going to bond with their partner in the way that the bases would.─── 調(diào)轉(zhuǎn)方向 新的核苷酸加入進來 他們將按照堿基配對 彼此結(jié)合起來

6 、Our acrobats are colourcoded according to which nucleotide they represent.─── 我們的雜技演員身著不同顏色 代表了不同的核苷酸

7 、The holoenzyme recognizes specific nucleotide sequences on the DNA duplex(promoters).───全酶還能識別DNA雙鏈分子上的特定核苷酸序列（起動基因）。

8 、A biotin-labeled DNA probe specific for hepatitis B virus(HBV)nucleotide sequences was hybridized in situ to liver tissue of 129 cases with liver disease.───應(yīng)用生物素標記HBV DNA(**病毒脫氧核糖核酸)作探針,對129例肝病患者肝組織作原位雜交研究。

9 、Single nucleotide polymorphisms(SNPs) is another new genetic marker studied after human genome project.───單核苷酸多態(tài)性是在人類基因組計劃后,進行研究的一項新的遺傳標記。

10 、There are two long chains of letters, or what we call bases, made up of nucleotides, of which there are four types.─── 兩條長鏈上有字母表示的堿基 一共四種

11 、They were the variation between individuals and populations because of single nucleotide base alteration, including transition, transversion, insertion and deletion.───它是由單個堿基的轉(zhuǎn)換、顛換、**入或缺失引起的點突變，使得群體之間和個體之間產(chǎn)生了差異。

12 、A nucleotide molecule that consists of a combination of two nucleotide units.───二核苷酸兩個單核苷酸結(jié)合而成的核苷酸分子

13 、When resistance occurs with an oral agent, I think you have to use combination therapy, most often with a nucleoside and nucleotide analogue.───當用口服藥物耐藥發(fā)生的時候，我想你最好使用聯(lián)合治療。最常是核苷和核苷酸類似物聯(lián)合應(yīng)用。

14 、The partial nucleotide sequence(185 bp)of the Roe deer Sry gene was determined by cloning the PCR product.───對Sry-PCR產(chǎn)物克隆測序,得到185bp的Sry基因部分核苷酸序列。

15 、Using the assay system of Ca2+-dependent cyclic nucleotide phosphodieste-rase (PDE), we observed the antagonistic effects of ligusterazine on calmodu-lin (CaM) .───實驗利用Ca~(2+)依賴性環(huán)核苷酸**酸二酯酶(PDE)測定方法,觀察川芎嗪拮抗鈣調(diào)素(CaM)的作用。

16 、Principal constituent: Nucleotide, linolenic acid, linoleic acid, skimmed milk, lactose, lactalbumin, ingredients and so on mineral substance, Vitamin, taurine.───主要成分：核苷酸、亞麻酸、亞油酸、脫脂奶，乳糖，乳清蛋白，礦物質(zhì)、維生素、氨基乙磺酸等成分。

17 、Each pair is made up of something called a nucleotide.─── 每對由核甘酸組成 只有四個核甘酸存在DNA里

18 、The nucleotide differences are9.7% between pADR-1 and ayw,9.3% between pADR-1 and adw,while therestill is about 2% dieffrence between pADR-1 and pHBr330 reported by Ono.───與已報道的ayw和adw亞型HBV DNA的核苷酸順序差異較大,分別為9.7%和9.3%。

19 、Nucleotide sequencing can tell if two people are infected with the same strain of herpes.─── 核苷酸序列可以證明 兩個人是否感染了同一菌株的皰疹

20 、The ionotrophic nucleotide receptor P2X(7) regulates compartmentalized acute inflammation and the immune response to airway pathogens.───親離子性核苷酸受體P2X(7)調(diào)節(jié)劃分急性炎癥的局限化和對氣道病原體的免疫反應(yīng)。

21 、The effects of adding mixture nucleotide (MN) on the micellization of DgP in aqueous, solution were studied by turbidimetry, differential scanning calorimetry (DSC) and DLS.───利用濁度法、示差掃描量熱法(DSC)和動態(tài)光散射研究了外加混合核苷酸(MN)對于DgP水溶液膠束化行為的影響。

22 、They then confirmed 30 suspected single nucleotide polymorphisms (SNPs) in nearly 22,000 women with breast cancer and a similar number of controls spanning 22 studies.───他們在橫跨22項研究將近22，000名乳腺癌女性和基本相同數(shù)目的對照婦女中發(fā)現(xiàn)了30個可疑的單核苷酸多態(tài)性位點。

23 、Classically, the nucleotide sequence in DNA has been considered as the sole driver of heredity.───傳統(tǒng)遺傳學(xué)認為，DNA的核苷酸序列是遺傳的唯一基礎(chǔ)。

24 、A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans.───pdf本站所有圖書及資料均可在子午學(xué)術(shù)論壇得到應(yīng)助下載。

25 、It also carries a specific nucleotide sequence, the anticodon.───它還帶有特定的核苷酸序列即反密碼子。

26 、His work showed that the inability to add nucleotide repeats to chromosomes led to telomere shortening and eventually cell death.───他的研究表明向染色體中添加核苷酸重復(fù)并不會導(dǎo)致端粒減短及最終的細胞死亡。

27 、A segment of double - stranded DNA in which the nucleotide sequence of one strand reads in reverse order to that of the complementary strand.───回文結(jié)構(gòu)含有雙股脫氧核糖核酸的一部分，其中的核苷酸系列的一股顛倒順序來讀取即為互補的一股

28 、Small mutations including single nucleotide substitutions,small insertions,and small deletions,are the major portion in genetic variations.───在基因突變中,小突變較大突變發(fā)生率要高。

29 、The second nucleotide in optimal human CpG motifs was thymidine, while in less active human CpG motifs or optimal murine CpG motifs, it was purines.───5′ GTCGTT 3′和 5′ GTCGTC 3′ 2個基序?qū)θ薆細胞有高度免疫刺激活性 ,第二位堿基均為“T” ,而在小鼠CpG基序中該位堿基為“G”或“A”。

30 、The complate nucleotide sequences of the cloned preS genes(preS-HZ and preS-LZ,GenBank accession numbers:Af325674 and AF325675 respectively) were 522bp long,encoding 174aa.───克隆的HBVpreS基因杭州分離物 (preS HZ)和蘭州分離物 (preS LZ)全長 5 2 2個核苷酸 ,編碼174個氨基酸。

31 、The whole nucleotide sequence of D2V-HN89 envelope gene was 1? 464bp. Nucleotide and amino acid homology were 95% and 98% respectively between D2V-HN89 and D2V-NGC.───D2V HN89株E基因核苷酸全長 146 4bp ,核苷酸和氨基酸序列與D2V NGC株的同源性分別為 95%和 98%,系統(tǒng)樹分析顯示其與登革 2型牙買加株及登革 2型巴西 90株的親緣關(guān)系最近。

32 、It had highest homologies with two isolates from Hangzhou,HZLB1 and HZLB2,which amounted to 98.7% and 99.0% at nucleotide level and 99.0% and 99.7% at amino acid level.───其中與中國浙江杭州蘿卜的兩個分離物HZLB1、HZLB2同源性最高,核苷酸序列的同源性為98.7%和99.0%,氨基酸序列同源性為99.0%和99.7%。

33 、LA strain had the highest nucleotide sequence similarity with WFL strain, as high as 96%, and LA strain also belonged to topotype Cathay, serotype O.───LA株與WFL株核苷酸序列相似性最高，達96%，也屬于O型的Cathay型毒株。

34 、Single nucleotide polymorphism(SNP) is a novel molecular marker, which refer to genetic variation from single nucleotide mutation.───單核苷酸多態(tài)性 (single nucleotide polymorphisms,SNPs)是一種新的分子標記 ,是指基因組由于單個核苷酸的變異所產(chǎn)生的差異。

35 、Nucleotide sequences homologous to oncornaviruses DNA products have been observed in human leukaemic cells.───在人白血病細胞中，已經(jīng)觀察到與腫瘤毒病DNA產(chǎn)物相同的核苷酸序列。

36 、Three single nucleotide polymorphism (SNP) sites, -28G/C and -403G/A in the promoter region, Inl.───已經(jīng)發(fā)現(xiàn)的3個主要RANTES基因單核苷酸多態(tài)性(SNP)位點是位于基因啟動子區(qū)的-403G/A、-28C/G變異和位于第一個內(nèi)含子區(qū)的第四軍醫(yī)大學(xué)得士學(xué)位論文翔. 目.

37 、Using high-density genomewide single nucleotide polymorphism (SNP) genotyping arrays, they identified a genetic locus associated with the disease.───他們使用高密度基因組單核苷酸多態(tài)性(SNP)基因序列方法，辨識與此病癥有關(guān)的基因位置；

38 、Ls-rRNA 5' nucleotide sequence of Rohdea japonica (Liliaceae) and its evolutionary significance.───萬年青 Ls-rRNA 5' 端核苷酸序列及進化意義.

39 、The newly identified substance proved to be a so called nucleotide, and was named cyclic adenosine phosphate or cyclic AMP.───同樣，還可以形成第**條件反射。在人身上則可以建立多級的條件反射。

40 、The DLA EIAV gag shared the homology of 80% in nucleotide and 84.47% in amino acid with the EIAV Wyoming 1369 strain.───與美國EIAVWyoming 136 9株比較 ,核苷酸同源性為 80% ,氨基酸同源性為 84 47%。

41 、You mean combination therapy or monotherapy? Nucleotide analogue with interferon combination?───你說的是聯(lián)合治療或者單藥治療嗎？核苷類似物聯(lián)合還是和干擾素聯(lián)合？

42 、The single nucleotide polymorphisms (SNP) of pituitary specific transcription factor 1(PIT-1)gene was analyzed in Xiang pig, Shanghai White pig and Yorkshire pig.───對香豬、上海白豬、大約克夏豬的垂體特異性轉(zhuǎn)錄因子(PIT-1)基因進行了單核苷酸多態(tài)性(SNP)分析。

43 、Furthermore, we found an important SNP (Single Nucleotide Polymorphism) at 725 position of the MC1R coding region.───另外發(fā)現(xiàn)牛MC1R基因編碼區(qū)725處存在一重要的SNP(單核苷酸多態(tài)性)。

44 、However, between two isolated strong virulent strains, there was a low homogeneity of 88.2% in nucleotide, and there was a high homogeneity of 93.9% in amino acid residue.───兩分離株核苷酸序列同源性較低,為88.2%,但氨基酸序列同源性較高,為93.9%。

45 、The nucleotide and deduced amino acid sequences of the six ORFs were aligned and compared with those of the MAV-PS1 isolate and PAV-aus.───它與MAV美國MAV-PS1分離物基因組序列同源性最高，全基因組為90.4%。

46 、Nucleotide similarities between the S1 gene of AVAV C-98 and that of ARV-176,MDRV-YJL,ARV-S1133 and ARV-138 were 99.9%,99.3%,97.9% and 81.2%,respectively.───與MDRV-YJL的同源性為99.3%,與弱毒疫苗株ARV-S1133的同源性也達97.9%; 與ARV-138株的同源性最低,為81.2%。

47 、Most genetic differences in people probably take the form of single nucleotide polymorphisms, or SNPs (pronounced “snips”), in which a single DNA letter substitutes for another.───人與人之間多數(shù)的基因差異，是以單核苷酸多型性（SNP）的形式出現(xiàn)；那是DNA上單一個堿基遭到替換所造成的。

48 、Ding. 2008.Association of single nucleotide polymorphism in the embryonic differentially expressed genes with reproductive traits in pigs.───臺灣土雞表現(xiàn)序列標簽序列庫之單一核苷酸多型性的偵測。

49 、Enormous obstacles block Gilbert's picture of RNA forming in a nonliving nucleotide soup.───吉爾伯特描繪RNA從無生命的核苷酸湯中形成的景象，有著巨大的障礙。

50 、A full-length cDNA of DFL and its antisense nucleotide sequence have been transformed into Nicotiana tabacum under the control of a cauliflower mosaic virus 35S promoter.───為了鑒定DFL基因的功能作用,構(gòu)建了由35S啟動DFL基因的正反義表達載體(載體中同時包含有由另外兩個35S啟動的潮霉素篩選基因和GUS組織化學(xué)染色基因)轉(zhuǎn)化煙草。

51 、Furthermore,DNA was also found to be made of nucleotide chains made of four bases,commonly represented by A,C,T,and G.───人們還發(fā)現(xiàn)，DNA由核苷酸鏈組成，而組成核苷酸鏈的是四種堿基，通常用A、C、T和G來代表。

52 、The record of EST database is more than 120,000.2. Nucleotide Sequences Extension System in silico (NSES) has been established.───其中,家蠶的:EST’數(shù)據(jù)庫中的記錄量超過了12萬。2.建立了核酸序列電子自動延伸系統(tǒng)。

53 、It contains bacteria-like organisms with distinctive ribosomal RNA whose nucleotide sequences differ significantly from those of other prokaryotes.───在現(xiàn)代的分類系統(tǒng)中，有自己的分類地位。

54 、The NCBI taxonomy database contains the names of all organisms that are represented in the genetic databases with at least one nucleotide or protein sequence.───NCBI的分類學(xué)數(shù)據(jù)庫包括所有遺傳數(shù)據(jù)庫里的生物體，這些數(shù)據(jù)至少含有一種核苷酸或蛋白質(zhì)序列。

55 、Nucleotide diversity in these 4 populations was Dai 1.52, Wa 1.38, Lahu 1.31and Tibetan 1.40 respectively.───4個群體的核酸多態(tài)度分別為傣族1.52，佤族1-38，拉祜1.31，藏族1.40，總多態(tài)度為1.39。

56 、Single nucleotide polymorphism plays an essential role in elucidating hereditary cardiovascular diseases.───因此單核苷酸多態(tài)性是闡明遺傳性心血管疾病的重要因素。

57 、DNA examination identified a missense mutation at nucleotide 134 of exon 5 of the SOD1 gene resulting in the aminoacid substitution serine-134-asparagine (S134N).───DNA檢查確定了SOD1基因第5外顯子的第134位核苷酸的錯義突變，導(dǎo)致了第134位的氨基酸由絲氨酸替換為天冬酰胺酸。

58 、But if the patients have cirrhosis, which means severe disease, then what we generally do is do not stop nucleoside or nucleotide analogue.───但是如果患者有肝硬化，這種嚴重的疾病時候，我們一般所要做的都是不要停止核苷酸或者核苷類似物等藥物。

59 、SNPs: Single Nucleotide Polymorphisms. (Image courtesy of the U.S. Department of Energy Human Genome Program.───單核甘酸變異。(影像提供:美國能源部人類基因組計劃。

60 、A nucleotide consisting of one molecule each of a phosphoric acid, a sugar, and either a purine or a pyrimidine base.───單核苷酸**酸、糖、嘌呤或嘧啶堿基中的一種，它組成的一個分子的苷酸

61 、The ORF encoding p10 was 261 nucleotide long and encoding a putative 87 amino acid polypeptide of 9.3 kD.───P10基因編碼區(qū)全長261bp，可編碼分子量為9.3kD，由87個氨基酸殘基組成的多肽。

62 、Tenofovir: Another nucleotide that is associated with a 4 log10 decrease in HBV viremia and is active against lamivudine-resistant strains.───太諾夫為：另一種核苷類似物，有4個數(shù)量級的HBV濃度降低，，對拉米抗藥株有效。

63 、SZ strain had the highest nucleotide sequence similarity with Tau-YuanTW97 strain, as high as 93%, so SZ strain should be classified to topotype Cathay, serotype O.───SZ株與Tau-YuanTW97株核苷酸序列相似性最高，達93%，屬于O型的Cathay型毒株；

64 、So analogs, including nucleoside and nucleotide analogs are now potent drugs, which suppress complicated viral replication of HVC, I will say in 70% to 90% of the patients.───因此，現(xiàn)在核苷類藥物是強效藥物，能抑制復(fù)雜的丙肝病毒復(fù)制，我認為能抑制70%到90%的患者。

65 、The reversible genes were particularly involved in xenobiotic functions (managing chemicals not produced in the body), nucleotide metabolism and mucus secretion.───可逆基因一般和異生物質(zhì)功能（管理不由身體產(chǎn)生的化學(xué)物質(zhì)）、核苷代謝、黏液分泌有關(guān)。

66 、Objective To explore the effect of exogenous purine nucleotide on the augmented atabolism of neurocyte nucleotide induced by morphine.───嗎啡在鎮(zhèn)痛的同時引起藥物依賴癥狀，因此老年慢性疼痛患者不建議長期使用此類藥物止疼。

67 、The recombinantpGEX-T-HEV has been successfully constructed, and HEV nucleotide of whichwas 92.9% homologous with that of the Burma strain of HEV (ET1.l).───與HEV緬甸株ET1.1的核苷酸序列比較，同源性為92.9%。 三、pGEX-4T-3-HEV重組體在大腸桿菌中的表達

68 、Eight cases have mutation from adenine (A) to cytosine (C) in 546th nucleotide and from asparagine (N) to threonine (T) in 131st amino acid residue.───8份序列均存在第546位核營酸從A到C的突變，使第131位氨基酸由天冬氨酞(N)變?yōu)樘K氨酸(T)。

69 、Adenosylcobalamin (coenzyme B12), for example, contains an entire RNA nucleotide, and thiamine pyrophosphate (coenzyme B1) carries around a piece of sugar-phosphate backbone.───舉例來說，維生素B12腺酶鈷胺（adenosylcobalamin）含有一個完整的RNA腺酶酸；

70 、One nucleotide acid fragment (350bp) was obtained in Brassica parachinensis Bailey and Brassica oleracea L. Var.───在49菜心和包菜中擴增到一條(350bp)核酸片段,而在芥蘭中擴增到兩條(350bp和466bp)核酸片段。

71 、There are big differences in the nucleotide and amino acid sequences of envelope, NS1 gene between B strain and NGC strain.───B株E、NS1基因序列和氨基酸序列與NGC株存在差異 ;

72 、It contains abundant dainty substances as nucleotide, guanylic acid, inosinic acid, polypeptide and amino acid, as well as plenty of vitamin B complex.───其核苷酸、鳥甘酸、肌苷酸及多肽和氨基酸等美味物質(zhì)異常豐富，還含有大量的維生素B群。

73 、Two strands of nucleotides, each with a strong backbone composed of sugar and phosphates, with what we call nucleotide bases on the inside.─── 兩條核苷酸鏈 每條鏈都擁有一個由糖類和**酸組成的堅實骨架 雙鏈內(nèi)部則是核苷酸堿基對

74 、Software solution that provides a visual interface to nucleotide mutations.───為核甘酸突變提供視覺介面的軟件解決方案。

75 、Single nucleotide polymorphisms are indiidual ariations in the DNA that are spaced across the human chromosomes.───單核苷酸多態(tài)性是指人類基因組范圍內(nèi)DNA的個體差異。

76 、In all of these samples there were 69 nucleotide variations and 67 haplo-types. There was 2.679 mutation sites on average per person.───共發(fā)現(xiàn)69個位點變異,平均每個個體存在2.679個堿基突變,檢出67個單倍型,基因多樣性為97.92%。

77 、The human CYP2B6 gene is highly polymorphic,having many single nucleotide polymorphisms in promoters and coding regions.───CYP2B6具有高度基因多態(tài)性,在基因編碼區(qū)和非編碼存在許多單堿基突變。

78 、By comparing with the published genomic sequence of AEV vaccine strain 1 143,there are 98% nucleotide and 97.6% amino acid identities between them.───與已發(fā)表的AEV疫苗株1143的基因組序列比較發(fā)現(xiàn),它們之間核苷酸和氨基酸的同源性分別為98%和97 6%。

79 、Compared with Eg101 strain, Chin-01 strain shows a nucleotide sequence identity of 97.3% and an amino acid sequence identity of 99.7%.───序列同源性分析表明 ,Chin_0 1株與埃及Eg10 1株高度同源 ,兩者氨基酸序列僅有 0 .3%的差異。

80 、The homology of Giardia canis virus to sequence of L13218(GenBank) was 94.62% in the nucleotide,and 93.50% in the amino acid levels.───其序列與國外報道的人源藍氏賈第蟲病毒(L13218)序列同源性為94.62%,編碼的氨基酸同源性為93.50%;

81 、FCY1 strain has more high divergence than WLD1.The difference of nucleotide sequence of the hly gene has not relationship with its trgion and source.───分離菌株WLD1和FCY1,尤其是FCY1分化程度較高,Lmhly基因核苷酸序列差異的距離與地理分布、菌株的樣品來源無相關(guān)性。

82 、Several of the agents that inhibit genome replication are nucleoside or nucleotide analogues, which resemble the building blocks of genes.───好幾種抑制基因復(fù)制的藥物是核苷或核苷酸的類似物，它們與基因的組成單位十分相似。

83 、Fig.3 Phylogenetic analysis of the3'- end nucleotide sequences of all available SYSV isolates rooted with OYDV( AJ510223).───圖3大蔥黃條病毒分離物基因組3’-末端區(qū)域核苷酸序列的系統(tǒng)進化樹分析，洋蔥黃矮病毒(J510223)為根殖序列。

84 、Single nucleotide polymorphisms (SNPs), the third-generation genetic marker, possess the characteristic of large numbers and dispersed distribution.───單核苷酸多態(tài)(Single-nucleotide polymorphism，SNP)作為第三代遺傳標記，具有數(shù)量大，分布廣的特點。

85 、However, no difference in t he nucleotide sequence of these exons was detected in all these selected PV pati ents who had different ...───但從我們選取的對維甲酸反應(yīng)性不同的尋常型銀屑病患者中,未發(fā)現(xiàn)彼此間外顯子堿基序列存在差異。

86 、DNA is extremely well suited to making such derivatives because every nucleotide along the helix has sites where molecules can be attached.───DNA極適合用來制造這些衍生物，因為DNA螺旋上的每一個核苷酸，都有許多位置可以接上外來分子。

遺傳變異縮寫？

遺傳變異是指基因組中的突發(fā)性或隨機性的變化。這些變異可以通過多種方式發(fā)生，如基因突變、基因重組等。遺傳變異是生物進化和適應(yīng)環(huán)境的重要驅(qū)動力之一。在遺傳學(xué)中，遺傳變異通常用縮寫"GV"來表示。

遺傳變異縮寫？

遺傳變異的縮寫是ycby